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The lumps antidote is used to cure the lumps. It is in the form of an orb that resembles a basketball-sized pearl. For the antidote to work, the infected individual must sit on it before sunset. When Finn first encounters the antidote it is situated at Makeout Point, where Monty, Glasses, and Lenny are taking turns sitting on it to become smooth. However, because they are already Lumpy Space People the smoothness wears off after they get off the orb. The lumps antidote is last seen on the ground at weekly Promcoming after Finn and Jake are cured of the lumps.
- The lumps antidote was formed from constant agitation in Lumpy Space. This is a reference to how oysters are agitated into making pearls.