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Nearly all inhabitants of Ooo are mutants. After the Mushroom War, the inhabitants of earth were either killed or mutated (Very few humans went unchanged). Centuries after the war, the surviving mutants have populated Ooo with the many bizarre species we see.
- Hyooman tribe
- Princess Princess Princess
- Candy People
- Freak City inhabitants
- Old Man Henchman
- Evil Monster
- The Lich
- Princess Bubblegum